Ketamine, Obesity, and Depression: How Are They’re Linked?

Obesity and Depression

Obesity and depression are 2 of the most common ailments affecting US citizens today. These citizens, as well as doctors, have been seeking the correlation between the two and successful alternative treatments. While ketamine has taken the mental health community by storm, its uses and research with an especially obese sample size haven’t been seen until recently. 

UAB Study

In the last two decades, the University of Alabama at Birmingham (UAB) used data from a 15-year study of 5,115 men and women ages 18-30 to seek answers. Participants were health screened for entry using the Body Mass Index (BMI). BMI is a calculation using one’s height and weight, (BMI = kg/m2 where kg is one’s weight in kg and m2 is height in meters squared.) The team of researchers continuously measured BMI waist sizes to find a correlation between waist BMI changes and changes in depressive states. In addition, during the trial, participants were asked to rank their own depression to track progress.

What They Found

The results concluded were somewhat expected but also enlightening. Such as, none of the participants reduced their waist BMIs during the 15-year study, whereas all gained overall weight. Furthermore, Doctors did notice that participants who started with a high waist BMI did not show an increase nor decrease in depression levels. 

By the end of the 15th year, the average waist BMI increase in more depressed participants was 2.6 centimeters more than the group who ranked lower on the depressive scale. In conclusion, it appears that abdominal weight and depression have a relationship. Food and exercise are still the king, they too play an enormous role in mental and physical health. 

Ketamine and Cortisol

An interesting find during studies such as these is that the stress hormone Cortisol may be closely linked to abdominal weight. Cortisol is our fear and stress mechanism, which can be helpful and harmful if levels become unnecessarily high. For this reason, ketamine therapy may be a perfect fit. Its ability to rapidly reduce cortisol levels is one reason its modern use as an antidepressant is gaining so much momentum. The future is bright thanks to researchers like The Neuroscienter for furthering the study of the mind.

Come See Us!

Both depression and obesity can make it tough to achieve changes in life. Often lack of energy or poof self-confidence can hinder you from recovery. There’s no better time than now and The Neuroscience Center is a comfortable, professional environment that has seen and helped it all. If obesity, depression, OCD, PTD or any other mood disorder is bothering you give us a call at 847-236-9310 or fill our form out at 

Michael Bryant

Michael Bryant

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